Journal Publications

Mundo, A.I., Greening, G.J., Fahr, M.J., Hale, L.N., Bullard, E.A., Rajaram, N., Muldoon, T.J., “Diffuse reflectance spectroscopy to monitor murine colorectal tumor progression and therapeutic response”, Journal of Biomedical Optics, 25(3) 035002 (2020) Download

Bess, S.N., Greening, G.J. Muldoon, T.J., “Efficacy and clinical monitoring strategies for immune checkpoint inhibitors and targeted cytokine immunotherapy for locally advanced and metastatic colorectal cancer,” Cytokine and Growth Factor Reviews, 49:1-9 (2019) Download

Greening, G.J., Mundo, A.I., Rajaram, N., Muldoon, T.J., “Sampling depth of a diffuse reflectance spectroscopy probe for in-vivo physiological quantification of murine subcutaneous tumor allografts,” Journal of Biomedical Optics, 23(8), 085006. (2018) Download

Greening, G.J., Miller, K.P., Spainhour, C.R., Cato, M.D., Muldoon, T.J., “Effects of isoflurane anesthesia on physiological parameters in murine subcutaneous tumor allografts measured via diffuse reflectance spectroscopy,” Biomedical Optics Express, 9(6), 2871-2886. (2018) Download

Tabassum, S., Pera, V., Greening, G.J., Muldoon, T.J., Roblyer, D., “Two-layer inverse model for improved longitudinal preclinical tumor imaging in the spatial frequency domain,” Journal of Biomedical Optics, 23(7), 076011. (2018) Download

Prieto, S.P., Lai, K.K., Laryea, J.A., Mizell, J.S., Mustain, W.C., Muldoon, T.J., “Fluorescein as a topical fluorescent contrast agent for quantitative microendoscopic inspection of colorectal epithelium,” Biomedical Optics Express, 8(4), 2324-2338. (2017) Download

Powless, A.J., Conley, R.J., Freeman, K.A., Muldoon, T.J., “Considerations for point-of-care diagnostics: evaluation of acridine orange staining and postprocessing methods for a three-part leukocyte differential test,” Journal of Biomedical Optics, 22(3), 035001. (2017) Download

Alhallak, K., Rebello, L.G., Muldoon, T.J., Quinn, K.P., Rajaram, N., “Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism,” Biomedical Optics Express, 7(11), 4365-4374. (2016) Download

Greening, G.J., Rajaram, N., Muldoon, T.J., “Multimodal imaging and spectroscopy fiber-bundle microendoscopy platform for non-invasive, in vivo tissue analysis,” Journal of Visualized Experiments, (116), e54564. (2016) Download

Greening, G.J., James, H.M., Dierks, M.K., Vongkittiargorn, N., Osterholm, S.M., Rajaram, N., Muldoon, T.J., “Towards monitoring dysplastic progression in the oral cavity using a hybrid fiber-bundle imaging and spectroscopy probe,” Scientific Reports, 6:26734. (2016) Download

Prieto, S., Lai, K., Laryea, J., Mizell, J., Muldoon, T.J., “Quantitative analysis of ex vivo colorectal epithelium using an automated feature extraction algorithm for microendoscopy image data,” Journal of Medical Imaging, 3(2), 024502. (2016) Download

Jenkins, S., Meeker, D., Miller, E., Beenken, K., Loughran, A., Powless, A., Muldoon, T.J., Galanzha, E., Zharov, V., Smeltzer, M.S., Chen, J.S., “Synergistic photothermal and antibiotic killing of biofilm-associated staphylococcus aureus using targeted, antibiotic-loaded gold nanoconstructs,” ACS Infectious Diseases, 2(4), 241–250. (2016) Download

Greening, G.J., James, H.J., Muldoon, T.J., “Optical Phantoms: Diffuse and sub-diffuse imaging and spectroscopy validation,” SPIE Spotlights, 1-40. (2016) Download

Greening, G.J., Powless, A.J., Hutcheson, J.A., James, H.M., Diekrs, M.K., Rajaram, N., Muldoon, T.J., “Fiber-bundle microendoscopy with sub-diffuse reflectance spectroscopy and intensity mapping for multimodal optical biopsy of stratified epithelium,” Biomedical Optics Express, 6(12), 4934-50. (2015) Download

Hutcheson, J.A., Majid, A.A., Powless, A.J., Muldoon, T.J., “A widefield fluorescence microscope with a linear image sensor for image cytometry of biospecimens: considerations for image quality optimization” Review of Scientific Instruments, 86(9), 093709. (2015) Download

Prieto, S.P., Powless, A.J., Boice, J.W., Sharma, S.G., Muldoon, T.J., “Proflavine hemisulfate as a fluorescent contrast agent for point-of-care cytology,” PLoS One, 10(5), 1-15. (2015) Download

Greening, G.J., Istfan, R., Higgins, L.M., Balachandran, K., Roblyer, D., Pierce, M.C., Muldoon, T.J., “Characterization of thin poly (dimethylsiloxane)-based tissue simulating phantoms with tunable reduced scattering and absorption coefficients at visible and near infrared wavelengths,” Journal of Biomedical Optics, 19(11), 115002. (2014) Download

Muldoon, T.J., Burgess, S., Chen, B., Ratner, D., Hillman, E.M.C., “Analysis of skin lesions using laminar optical tomography,” Biomedical Optics Express, 3(7), 1701-1712. (2012) Download

Muldoon, T.J., Roblyer, D., Williams, M.D., Stepanek, V.M.T., Richards-Kortum, R., Gillenwater, A.M. “Non-invasive imaging of oral neoplasia with a high-resolution fiber optic microendoscope.” Head and Neck, 34(3), 305-312. (2012) Download

Thekkek, N., Muldoon, T.J., et al. “Vital-dye enhanced fluorescence imaging of gastrointestinal mucosa: metaplasia, neoplasia, inflammation.” Gastrointestinal Endoscopy, 75(4), 877-87. (2012) Download

Rosbach, K., Shin, D., Muldoon, T.J., et al. “High-resolution fiber optic microscopy with fluorescent contrast enhancement for the identification of axillary lymph node metastases in breast cancer: a pilot study.” Biomedical Optics Express. 1(3), 911-922. (2010) Download

Muldoon, T.J., Thekkek, N., Roblyer, D., et al. “Evaluation of quantitative image analysis criteria for the high-resolution micro-endoscopic detection of neoplasia in Barrett’s esophagus,” Journal of Biomedical Optics, 15(2): 026027. (2010) Download

Nitin, N., Carlson, A.L., Muldoon, T.J., et al. “Molecular imaging of glucose uptake in oral neoplasia following topical application of fluorescently labeled deoxy-glucose,” International Journal of Cancer, 124(11), 2634-42. (2009) Download

Muldoon, T.J., Anandasabapathy, S., Maru, D., and Richards-Kortum, R. “High-resolution imaging in Barrett’s Esophagus: a novel, low-cost endoscopic microscope,” Gastrointestinal Endoscopy, 68(4), 737-44. (2008) Download

Muldoon, T.J., Pierce, M., Nida, D., Williams, M., Gillenwater, A. and Richards-Kortum, R. “Subcellular-resolution molecular imaging within living tissue by fiber microendoscopy,” Optics Express, 15(25), 16413-16423. (2007) Download

Proceedings Papers

Mundo, A.I., G.J. Greening, and T.J. Muldoon, Characterization of a multimodal endoscopically deployable veterinary spectroscopy and imaging probe to determine therapeutic response in a murine orthotopic tumor model. SPIE BiOS. Vol. 10890. 2019: SPIE.  

Prieto, S.P., Greening, G.J., Lai, K.K., Muldoon, T.J., “Quantitative structural markers of colorectal dysplasia in a cross sectional study of ex vivo murine tissue using label-free multiphoton microscopy,” Proceedings of SPIE, Vol. 9712. (2016) Download

Powless, A.J., Feekin, L.E., Hutcheson, J.A., Alapat, D.V., Muldoon, T.J., “Low-cost computing and network communication for a point-of-care device to perform a 3-part leukocyte differential,” Proceedings of SPIE, Vol. 9715. (2016) Download

Greening, G.J., Rajaram, N., Muldoon, T.J., “In vivo measurement of non-keratinized squamous epithelium using a spectroscopic microendoscope with multiple source-detector separations,” Proceedings of SPIE, Vol. 9715. (2016) Download

Hutcheson, J.A., Khan, F.Z., Powless, A.J., Benson, D., Hunter, C.J., Fritsch, I., Muldoon, T.J., “A light sheet confocal microscope for image cytometry with a variable linear slit detector,” Proceedings of SPIE, Vol. 9720. (2016) Download

Prieto, S.P., Powless, A.J., Lai, K.K., Laryea, J.A., Mizell, J.S., Muldoon, T.J., “Qualitative and quantitative comparison of colonic microendoscopy image features to histopathology,” Proceedings of SPIE, Vol. 9328. (2015) Download

Powless, A.J., Jenkins, S.V., McKay, M.L., Chen, J., Muldoon, T.J., “Molecule-specific darkfield and multiphoton imaging using gold nanocages,” Proceedings of SPIE, Vol. 9339. (2015) Download

Greening, G.J., Powless, A.J., Hutcheson, J.A., Prieto, S.P., Majid, A.A., Muldoon, T.J., “Design and validation of a diffuse reflectance and spectroscopic microendoscope with poly (dimethylsioxane)-based phantoms,” Proceedings of SPIE, Vol. 9332. (2015) Download

Hutcheson, J.A., Powless, A.J., Majid, A.A., Claycomb, A., Fritsch, I., Balachandran, K., Muldoon, T.J., “High-throughput microfluidic line scan imaging for cytological characterization,” Proceedings of SPIE, Vol. 9320. (2015) Download

Pierce, M.C., Schwarz, R.A., Rosbach, K., Roblyer, D., Muldoon, T.J., et al. “Wide-field and high-resolution optical imaging for early detection of oral neoplasia,” Proceedings of SPIE, Vol. 7548C-68. (2010) Download

Richards-Kortum, R., Pierce, M., Vestewig, L., Muldoon, T.J., Rahman, M., “Global approaches to cancer prevention,” SPIE Newsroom, (2009) Download